Anti-TAPBP Antibody

Rabbit polyclonal reagents from Antibodies.com offer researchers a precise tool for investigating antigen presentation biology. This unconjugated primary antibody targets TAPBP (tapasin), the glycoprotein that bridges MHC class I molecules to the TAP peptide transporter in the endoplasmic reticulum and supports peptide loading onto nascent MHC class I complexes.

Validated for Western blot and immunohistochemistry workflows, the reagent recognizes both human and mouse targets, enabling translational studies across model systems and patient-derived tissue samples. The antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, packaged in a 100 µl volume.

Researchers studying tumor immune evasion, viral interference with MHC class I surface expression, or autoimmune pathways involving peptide-loading complex assembly commonly use this reagent. Preparing working aliquots before freezing reduces freeze-thaw cycling and helps preserve antibody activity over extended projects.