Anti-TAP Antibody

The TAP protein (Transporter Associated with Antigen Processing) is a key component of the MHC class I peptide-loading machinery, shuttling cytosolic peptide fragments into the endoplasmic reticulum for presentation to cytotoxic T lymphocytes. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human TAP target and is supplied as a 100 µl aliquot validated for western blot and immunofluorescence workflows on human samples and cell lines. Researchers apply the antibody to characterize antigen presentation defects, viral immune escape mechanisms, and tumor cell surface phenotype studies. For short-term use, refrigerate the antibody; for longer storage, freeze at -20 °C in working aliquots to preserve activity across multiple freeze-thaw cycles. The polyclonal format increases the likelihood of recognizing multiple epitopes on the transporter complex, improving robustness across denaturing (WB) and native fixation (IF) protocols.