Anti-TAL1 Antibody

TAL1 (T-cell acute lymphoblastic leukemia 1) is a basic helix-loop-helix transcription factor essential for early hematopoietic specification and vascular development. This unconjugated rabbit polyclonal IgG antibody from Antibodies.com was raised against the human TAL1 protein and is supplied at 200 µl for western blot detection of endogenous TAL1 in cell lysates. The reagent is reactive with human TAL1, supporting studies of leukemogenesis and normal blood cell differentiation. TAL1 is best known for its aberrant activation in T-cell acute lymphoblastic leukemia, where chromosomal rearrangements place TAL1 under ectopic regulatory control. Researchers investigating transcription factor networks in hematopoiesis or leukemia cell lines such as Jurkat and K562 can use this primary antibody in western blot protocols following standard RIPA lysis or SDS-sample buffer preparation of whole-cell extracts. The polyclonal host rabbit format recognizes multiple epitopes across the human TAL1 protein, which can improve signal consistency across experimental batches and reduce the impact of point mutations. Storage at -20 °C with aliquoting to limit freeze-thaw cycles preserves activity for downstream immunoblotting.