Anti-TAF9 Antibody

TAF9 (~29 kDa; also called TAFII31/TAFII32) sits at the core of multiple chromatin and transcription complexes, including TFIID, TFTC, STAGA, and the PCAF histone acetylase complex. Antibodies.com raises this affinity-purified polyclonal IgG reagent in rabbits to detect that subunit in its unconjugated form, supplied as a 200 µL liquid aliquot validated for Western blot and immunohistochemistry on human and rat samples.

The TAF9 subunit bridges TBP and other TBP-associated factors across RNA polymerase II core promoters, and it binds transcriptional activators such as p53 and VP16, making it a useful marker for studies of TFTC and STAGA complex assembly, histone acetylation, coactivator recruitment, and downstream gene expression control in mammalian systems. Researchers apply this antibody to map transcription-coupled signaling and altered TAF9 function implicated in neurodegenerative disease models.

Because the reagent is supplied unconjugated, it slots into standard immunodetection pipelines run with HRP- or biotin-labeled secondary antibodies. For reliable long-term stability, aliquot upon receipt, store frozen at -20 °C, and protect the preparation from repeated freeze-thaw cycles to preserve binding activity across downstream applications.