Anti-TAF15 Antibody

This polyclonal antibody from Antibodies.com specifically targets TAF15 (TATA-box binding protein associated factor 15), a member of the FET family of RNA-binding proteins involved in transcription initiation, pre-mRNA splicing, and the cellular DNA damage response. Raised in rabbit and supplied as an unconjugated reagent in a 100 µl volume, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples. TAF15 resides predominantly in the nucleus, where it contributes to the assembly of transcription complexes and to RNA processing events; aberrant FET-family activity has been documented in oncogenic fusion transcripts and in neurodegenerative disease models, so reliable immunological detection of the endogenous protein supports a broad range of molecular biology and pathology studies. The polyclonal format offers recognition of multiple epitopes across the TAF15 sequence, helping to maintain consistent signal intensity on immunoblots of whole-cell lysates and in chromogenic or fluorescent staining of formalin-fixed, paraffin-embedded tissue sections.