Anti-TACR1 Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets TACR1, the tachykinin receptor 1 G protein-coupled receptor that serves as the principal binding site for the neuropeptide substance P. The antibody is supplied as a 100 µL liquid aliquot of antiserum validated for Western blot and immunohistochemistry on human, mouse, and rat samples.

TACR1 is expressed across the central and peripheral nervous system and on selected immune cell populations, where it contributes to pain transmission, neurogenic inflammation, emetic signaling, and airway smooth muscle contraction. Researchers studying these pathways use the reagent to localize receptor distribution in fixed tissue sections and to identify the receptor band in membrane and whole-cell lysate preparations.

As a polyclonal reagent, the antibody recognizes multiple epitopes across the receptor, which can be advantageous when probing splice variants or truncated forms of the target. The unconjugated format allows investigators to pair it with their preferred secondary antibody and detection system, supporting both standard immunohistochemistry workflows and fluorescence readouts in multicolor panels.