Anti-TACC3 Antibody

This rabbit polyclonal IgG antibody from Antibodies.com recognizes the TACC3 protein, a centrosomal and mitotic spindle-associated factor required for kinetochore-microtubule attachment during cell division. Raised in rabbit and supplied as 100 µl of unconjugated reagent, it is validated for Western blot detection of the human target in research settings. TACC3 (Transforming Acidic Coiled-Coil Containing Protein 3) is frequently investigated in oncology, where elevated expression has been linked to breast, lung, and colorectal carcinomas, and in cell biology studies of chromosome segregation, centriole maturation, and the spindle assembly checkpoint. The polyclonal format offers multi-epitope recognition, which can improve sensitivity when probing low-abundance or post-translationally modified TACC3 species in cell lysates and tissue homogenates. Short-term storage at 4 °C is suitable for routine use, while aliquoting and freezing at -20 °C helps preserve antibody activity through repeated freeze-thaw cycles. Researchers commonly apply this reagent to human cell lines and primary tumor samples to examine mitotic progression, centrosome duplication, and the DNA damage response.