Anti-TAC3 Antibody

Tachykinin Precursor 3 (TAC3) encodes the neuropeptide precursor that gives rise to neurokinin B (NKB), a tachykinin implicated in hypothalamic signaling and the central neuroendocrine control of reproduction. This Antibodies.com rabbit polyclonal antibody targets the TAC3 protein and is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizer, in a 100 µl vial format. The unconjugated reagent is validated for Western blot (WB) and immunohistochemistry (IHC), with reactivity confirmed against Human, Mouse, and Rat samples, supporting translational work that bridges rodent models and human hypothalamic tissue. TAC3 is expressed by neurons of the infundibular (arcuate) nucleus, often in concert with kisspeptin, and loss-of-function mutations in TAC3 have been linked to normosmic idiopathic hypogonadotropic hypogonadism, so the antibody is useful for mapping NKB-expressing neuron populations and for probing precursor protein abundance in neuroendocrine tissue. For storage, aliquot and store at -20 °C, protect from light, and limit freeze-thaw cycles to preserve reagent activity for downstream chemiluminescent or chromogenic detection workflows.