Anti-TAB1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets TAB1, the TAK1-binding protein 1 (also known as MAP3K7IP1) that acts as an adaptor for TAK1 (MAP3K7) kinase in innate immune and inflammatory signaling cascades. The unconjugated reagent is raised in rabbit and recognizes the human TAB1 protein, supporting detection of endogenous TAB1 in cell lysates and tissue specimens.

Validated for western blot (WB) and immunohistochemistry (IHC) workflows, the antibody is widely used to investigate TAK1-mediated NF-κB and MAPK pathway activation, TGF-β signaling, and cytokine-driven inflammatory responses. As a polyclonal reagent, it recognizes multiple epitopes on TAB1, providing reliable signal across denatured samples for WB and fixed sections for IHC. The product is supplied as 100 µl of unconjugated antiserum; for routine use, keep refrigerated, and aliquot before freezing for long-term storage to limit repeated freeze-thaw cycles.

Investigators in signal transduction, innate immunity, and inflammation research will find this reagent useful for profiling TAB1 expression and studying its complex formation with TAK1 in human cell lines and primary tissue samples.