Anti-Synuclein-pan Antibody

Raised in rabbit, this polyclonal primary antibody recognizes conserved regions shared across alpha-, beta-, and gamma-synuclein, offering researchers studying neurodegeneration, synaptic vesicle dynamics, and Parkinson's disease pathology a single reagent for the whole synuclein family. The unconjugated preparation supports flexible pairing with secondary detection reagents and custom labeling workflows in Western blot and immunohistochemistry on human, mouse, and rat samples. Supplied as a 100 µl liquid stock, the antibody can be diluted into standard immunoblotting and blocking buffers; for routine handling, refrigerate upon receipt and aliquot before freezing for longer-term storage. Applied to brain tissue sections, the reagent highlights Lewy bodies and other alpha-synuclein inclusions characteristic of synucleinopathies, while Western blot workflows reveal the characteristic synuclein band pattern. Because the antibody recognizes shared epitopes across the family, it complements isoform-specific antibodies when mapping expression changes across disease models and transgenic lines. Antibodies.com supplies this reagent as part of its primary antibody portfolio, supporting neuroscience, cell biology, and protein aggregation research workflows.