Anti-Synuclein-pan (A19) Antibody

Antibodies.com supplies a rabbit polyclonal antibody directed against Synuclein-pan (A19). The reagent is provided unconjugated at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide, at approximately pH 7.2. It is validated for Western blot (WB) and immunohistochemistry (IHC), and reacts with Human, Mouse, and Rat samples.

Generation employed a synthetic peptide corresponding to amino acids at the N-terminus of Synuclein-α (residues 19–30) as the immunogen. The antibody detects endogenous levels of Synuclein-pan (α-synuclein, β-synuclein, γ-synuclein) protein, the target of which has a molecular weight of approximately 18 kDa. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using the epitope-specific immunogen, with purity reported as greater than 95% by SDS-PAGE.