Anti-Synuclein-α Antibody

Primary antibody from Antibodies.com raised against Synuclein-α, a 140-amino-acid presynaptic protein strongly implicated in Parkinson disease and related synucleinopathies. The reagent is a Rabbit polyclonal antibody supplied as 100 µl of unconjugated antiserum, validated for western blot, immunohistochemistry, and ELISA workflows on Human, Mouse, and Rat samples. Investigators studying Lewy body pathology, dopaminergic neurodegeneration, and protein aggregation rely on this reagent to probe endogenous Synuclein-α in brain tissue lysates and fixed neural sections. The polyclonal format recognizes multiple epitopes of the ~14 kDa monomer as well as higher-molecular-weight aggregated species that accumulate in affected neurons. Aliquot the reagent upon arrival, store refrigerated between uses, and limit freeze-thaw cycles to preserve binding activity across long-running IHC and immunoblotting campaigns.