Anti-Synuclein-α Antibody

This rabbit polyclonal antibody targets alpha-synuclein, a 140 amino acid presynaptic protein implicated in Parkinson's disease and related synucleinopathies. Raised in rabbit and supplied as an unconjugated reagent at 100 µl, it is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows across human, mouse, and rat samples.

Alpha-synuclein accumulates in Lewy bodies, and reliable immunological detection of the endogenous protein is central to neuroscience and neurodegeneration research. The antibody binds the target in tissue sections and cell lysates, supporting studies of dopaminergic neuron biology, protein aggregation kinetics, and disease modeling in synucleinopathy systems. Its polyclonal format allows recognition of multiple epitopes, which can be advantageous when probing truncated or post-translationally modified forms of the protein.

From Antibodies.com, this primary antibody is intended for research use only and fits laboratories investigating synaptic vesicle dynamics, mitochondrial dysfunction in Parkinson's models, and biomarker discovery in neurodegenerative disease.