Anti-SYNJ2 Antibody

Produced in rabbit as a polyclonal IgG, this unconjugated primary antibody targets SYNJ2 (Synaptojanin 2), a phosphoinositide phosphatase involved in clathrin-mediated endocytosis and actin cytoskeleton remodeling. SYNJ2 hydrolyzes the 5' phosphate of phosphatidylinositol 4,5-bisphosphate (PIP2), regulating membrane trafficking and cellular migration pathways relevant to neuronal signaling and certain cancer cell behaviors. The reagent is validated for Western blot (WB) on human samples and is supplied at 200 µL volume. Researchers studying synaptic vesicle recycling, phosphoinositide metabolism at nerve terminals, or SYNJ2's documented roles in tumor cell motility and invasion can use this antibody to detect endogenous SYNJ2 protein in lysates from human cell lines and primary tissue. The polyclonal format offers multiple epitope recognition, useful when working with truncated or post-translationally modified SYNJ2 variants. Antibodies.com provides this reagent as an unconjugated antisera, allowing flexible selection of secondary labels and chemiluminescent substrates for Western blot detection.