Anti-Synaptotagmin Antibody

Raised in rabbit and purified by affinity-chromatography against the epitope-specific immunogen, this polyclonal reagent from Antibodies.com is supplied as a 50 µl liquid formulation at 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, and it is unconjugated for flexible downstream labelling. The antibody was generated against a synthesized peptide derived from human Synaptotagmin 1/2 around the non-phosphorylation site of S309/306, and it specifically detects endogenous levels of Synaptotagmin protein in human, mouse and rat samples, making it a reliable pan-neuronal marker across these species. Validated applications include Western Blot (WB), Immunohistochemistry (IHC) and ELISA, covering both denatured and native detection workflows in neural and synaptic vesicle research. The polyclonal format ensures recognition of multiple epitopes on the target, which is particularly useful for detecting synaptic vesicle proteins where epitope masking can occur. The product is shipped refrigerated from the supplier's facility and is intended for research use only; for long-term stability it should be stored at -20 °C in small aliquots to avoid repeated freeze-thaw cycles, while avoiding the sodium azide when planning any future HRP or live-cell conjugation. Suitable for neuroscience, cell biology and neuropathology laboratories, this reagent offers a cost-effective option for labs working on synaptic transmission, neurotransmitter release and vesicle trafficking studies.