Anti-Synaptophysin Antibody [S7]

The S7 clone from Antibodies.com is a mouse monoclonal IgG1 antibody that recognizes the cytoplasmic domain of synaptophysin (SYP), a ~38 kDa integral membrane glycoprotein localized to presynaptic vesicles of neurons and neuroendocrine cells.

Supplied as 100 ug of liquid antibody in a single vial, the reagent is validated for western blot detection of endogenous synaptophysin in mouse and rat tissue lysates, including brain homogenates and neuroendocrine cell lines used to study synaptic vesicle biogenesis, neurotransmitter release, and neuronal differentiation.

Store at -20 degrees C in single-use aliquots to limit freeze-thaw cycles, and protect from light. The unconjugated format allows flexible pairing with HRP- or fluorophore-conjugated secondary antibodies, making this clone broadly useful for downstream immunoblotting, densitometric quantification of synaptic marker expression, and characterization of neuronal and neuroendocrine tumor models.