Anti-SYCP3 Antibody

This polyclonal reagent from Antibodies.com targets SYCP3 (Synaptonemal Complex Protein 3), a structural component of the synaptonemal complex that mediates homologous chromosome pairing, synapsis, and recombination during meiotic prophase I. Raised in rabbits and supplied as an unconjugated 100 µL liquid aliquot, the antibody is validated for Western blot and immunohistochemistry on human tissue and is widely used in studies of spermatogenesis, germ cell differentiation, and meiotic chromosome dynamics. Because SYCP3 expression is largely restricted to meiotic germ cells in testis tissue, it serves as a reliable marker for tracking pachytene progression, synaptonemal complex assembly, and crossover intermediates. Researchers investigating male infertility, gonadal development, and DNA double-strand break repair pathways have applied this reagent to paraffin-embedded and cryosectioned human testicular biopsies, where it produces discrete nuclear staining of spermatocytes. The polyclonal format provides multi-epitope recognition, strengthening signal when individual epitopes are partially masked by fixation or chemical crosslinking. For optimal antibody stability, refrigerate the vial between uses, aliquot to limit freeze-thaw cycles, and protect from light.