Anti-SUV39H2 Antibody

Generated in rabbit and affinity-purified as a polyclonal reagent, this unconjugated IgG antibody recognizes SUV39H2, a histone H3 lysine-9 methyltransferase that catalyzes H3K9 trimethylation at pericentric heterochromatin and contributes to transcriptional silencing.

Supplied by Antibodies.com in a 100 µl vial, the reagent is validated for Western blot and immunohistochemistry workflows and cross-reacts with both human and mouse samples. Researchers studying heterochromatin maintenance, DNA methylation coupling, repeat-element silencing, and SUV39H1/H2 compensation commonly use this antibody to probe endogenous protein levels in whole-cell lysates and to localize SUV39H2 in fixed tissue sections.

The polyclonal format broadens epitope coverage across the target, which is helpful when probing post-translational modifications or interaction partners in chromatin-enriched fractions. For short-term use, aliquot and refrigerate; for longer storage, freeze and limit freeze-thaw cycles to preserve antibody activity.