Anti-SUMO3 Antibody

Small Ubiquitin-like Modifier 3 (SUMO3) is a member of the ubiquitin-like protein family involved in post-translational SUMOylation, a pathway that regulates protein stability, nuclear trafficking, and cellular stress responses. The polyclonal antibody from Antibodies.com is raised in rabbit and supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 15 mM sodium azide at approximately pH 7.2, packaged as a 100 µl single-use vial.

This unconjugated primary antibody is validated for Western Blot (WB) detection of SUMO3 in human, mouse, and rat samples, enabling cross-species comparison of SUMO conjugation in cell lysates, tissue homogenates, and recombinant expression systems. Polyclonal recognition across multiple epitopes supports detection of both free SUMO3 and SUMO3 covalently attached to substrate proteins, which is useful when comparing modification states under different experimental conditions.

Research applications include profiling SUMOylation dynamics during cellular stress, mapping transcriptional regulators, and characterizing substrate modification in signaling pathways. The reagent is provided as a liquid aliquot intended for pairing with horseradish peroxidase (HRP) or fluorescent secondary antibodies for chemiluminescent or fluorescence readouts.