Anti-SUMO1 Antibody

Raised in rabbit against the SUMO1 target, this unconjugated polyclonal reagent is supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. It has been validated for western blot, immunohistochemistry, immunocytochemistry, immunofluorescence, and immunoprecipitation workflows across human, mouse, and rat samples. SUMO1 is a ~11.5 kDa ubiquitin-like modifier that is covalently conjugated to lysine residues on substrate proteins during SUMOylation, a post-translational modification that influences nuclear-cytoplasmic transport, transcriptional control, DNA damage response, and protein turnover. The unconjugated format allows investigators to couple the antibody to their own fluorophores, biotin, or HRP depending on the experimental design, supporting detection across multiple platforms. Each lot is provided by Antibodies.com as a liquid formulation in PBS buffer with the cryoprotectant glycerol, suitable for short-term storage at 4°C with longer term aliquoting at -20°C to minimize freeze-thaw cycles. Researchers studying post-translational modification pathways, cancer biology, stress response signaling, and chromatin regulation will find this reagent useful for examining both free and conjugated SUMO1 pools in cell lysates and fixed tissues.