Anti-SUMO Tag Antibody

The Anti-SUMO Tag Antibody from Antibodies.com is a mouse monoclonal IgG1 reagent supplied as a 100 µg liquid formulation, unconjugated and validated for Western blot detection of SUMO fusion proteins. SUMO (Small Ubiquitin-like Modifier) tags are widely fused to recombinant proteins to improve solubility and proper folding during bacterial expression, and this antibody recognizes SUMO-1 as well as the closely related SUMO-2 and SUMO-3 isoforms, allowing straightforward verification of expression constructs and cleavage by SUMO proteases. On standard SDS-PAGE blots, the antibody typically visualizes a band near 12 kDa, consistent with the size of the native SUMO moiety, and is commonly paired with His-tag purification workflows to confirm successful tag removal after Ulp1 digestion. Store working aliquots at -20 °C in a manual defrost freezer and limit repeated freeze-thaw cycles to preserve binding activity over the product shelf life.