Anti-SULT2B1 Antibody

The sulfotransferase enzyme SULT2B1 plays a central role in steroid and cholesterol metabolism, where it catalyzes the transfer of sulfonate groups to hydroxysteroids such as pregnenolone and DHEA. Produced in rabbits and affinity-purified for high specificity, this unconjugated polyclonal reagent from Antibodies.com targets the human SULT2B1 protein and is validated for Western blot and immunohistochemistry workflows on cell lysates and fixed tissue sections.

The 100 µl aliquot is supplied as a ready-to-use liquid in a single vial, allowing flexible dilution across multiple experimental setups. Researchers studying keratinocyte differentiation, epidermal barrier formation, hepatic cholesterol clearance, or the sulfation pathways implicated in prostate and breast tumor biology rely on this reagent to detect endogenous SULT2B1 expression. The unconjugated format supports downstream detection with a broad choice of secondary antibodies and either fluorophore or enzyme conjugates.

For optimal performance, aliquot the antibody upon arrival and store at -20 °C in working volumes to limit freeze-thaw cycles; avoid repeated cycles to preserve binding activity, and protect from light during handling. Each lot is stringently QC-tested against the human target, and the polyclonal mixture captures multiple epitopes across the SULT2B1 sequence, increasing the likelihood of robust signal even when one epitope is masked by sample preparation. This Human reactivity profile makes the antibody well suited to translational studies linking altered sulfotransferase activity to dermatological, hepatic, and oncological phenotypes.