Anti-Sulfite oxidase,mitochondrial Antibody

Generated in rabbit hosts, this unconjugated polyclonal antibody from Antibodies.com targets sulfite oxidase, a molybdenum- and heme-containing enzyme anchored in the mitochondrial intermembrane space where it catalyzes the terminal reaction of sulfur amino acid catabolism. The enzyme converts sulfite to sulfate using cytochrome c as the physiological electron acceptor, and loss-of-function mutations in the SUOX gene cause isolated sulfite oxidase deficiency, a severe neurometabolic disorder presenting in infancy. This reagent is validated for Western blot and immunohistochemistry on human samples and is supplied at 100 µg per vial, with each lot tested to confirm specificity. Researchers working on mitochondrial respiratory chain disorders, molybdenum cofactor biosynthesis, or sulfur metabolism use this antibody to probe endogenous SUOX expression in tissue sections, cell lysates, and subcellular fractions. For best results, store at -20 °C in working aliquots to limit freeze-thaw cycles and preserve binding activity.