Anti-STX3 Antibody

This polyclonal antibody from Antibodies.com targets Syntaxin-3 (STX3), a plasma membrane t-SNARE protein that mediates vesicle docking and fusion during exocytosis. STX3 plays a critical role in epithelial apical membrane trafficking, insulin granule exocytosis in pancreatic beta cells, mucus secretion in goblet cells, and neurotransmitter release. The reagent is raised in rabbit and supplied as an IgG isotype in an unconjugated format, packaged as 50 µl aliquots. Validated for Western Blot application, it recognizes endogenous STX3 in human, mouse, and rat samples, supporting comparative studies across model organisms. STX3 dysfunction has been linked to retinal degeneration, microvillus inclusion disease, and metabolic disorders, making this antibody useful for research in cell biology, neuroscience, ophthalmology, and metabolic disease. As a primary antibody, it is suited for detecting STX3 in lysates from tissues with active secretory pathways, including kidney, brain, and pancreas.