Anti-Stefin B Antibody

Stefin B (cystatin B, CSTB) is an intracellular cysteine cathepsin inhibitor studied in connection with Unverricht-Lundborg disease, a progressive myoclonus epilepsy syndrome, as well as in neurodegeneration and tumor biology research. Antibodies.com provides this affinity-purified reagent as a rabbit polyclonal antibody raised against the Stefin B target, supplied unconjugated in a 100 µl vial suitable for multiple downstream assays. Validated uses include western blot for protein detection in human, mouse, and rat lysates, immunohistochemistry for tissue localization work, and immunofluorescence for subcellular distribution imaging in cultured cells and fixed sections. Because the polyclonal host response recognizes multiple epitopes on the Stefin B polypeptide, the reagent supports investigations of protease regulation, lysosomal cathepsin balance, and altered cystatin expression tied to disease models.