Anti-STEAP4 Antibody

STEAP4 (also called STAMP2 and TNFAIP9) is a six-transmembrane epithelial metalloreductase involved in cellular iron and copper handling, and this Antibodies.com polyclonal antibody provides a western blot-validated reagent for tracking its expression in human, mouse, and rat samples. The antibody is raised in rabbit, is unconjugated for flexible secondary pairing, and is supplied in a 100 µL vial at 1 mg/mL in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3.

Researchers in metabolic disease, inflammation, and oncology use STEAP4 western blot detection to follow induction by TNFα and IL-6 in cultured adipocytes and hepatocytes, to study its dysregulation in obesity, type 2 diabetes, non-alcoholic fatty liver disease, and prostate or breast cancer tissue, and to compare expression across human, mouse, and rat model systems. Because the reagent is unconjugated, it can be paired with HRP-, biotin-, or fluorophore-conjugate secondaries for chemiluminescent or fluorescent western blot imaging without further preparation.

For storage, keep the vial refrigerated at 4°C for short-term use or aliquot and freeze at -20°C for longer-term retention; avoid repeated freeze-thaw cycles to preserve the 1 mg/mL stock. The included sodium azide inhibits microbial contamination and the solution can be diluted directly into assay buffer at typical western blot working concentrations.