Anti-STEAP4 Antibody

This unconjugated rabbit polyclonal IgG antibody targets STEAP4 (Six-Transmembrane Epithelial Antigen of Prostate 4), a metalloreductase that participates in iron and copper reduction at the plasma membrane and modulates inflammatory and metabolic signaling cascades. Produced by Antibodies.com, the reagent is validated for Western blot and immunohistochemistry workflows and detects the endogenous protein in human and mouse samples, supporting studies of adipose tissue biology, obesity-linked insulin resistance, prostate and breast tumor models, and innate immune responses in which STEAP4 transcript levels are dynamically regulated by TNF-α and related cytokines.

Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody is unconjugated and of the IgG isotype, leaving the choice of label and secondary detection reagent entirely to the end user. Researchers apply it to lysates from differentiated adipocytes, hepatic tissue sections, and tumor microarrays to investigate STEAP4-mediated metal homeostasis and downstream effects on glucose transporter trafficking and ferroptotic sensitivity.