Anti-STAT6 (Ab-645) Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes STAT6 (Signal Transducer and Activator of Transcription 6) at the epitope surrounding tyrosine 645, a phosphorylation site central to IL-4 and IL-13 signal transduction through the JAK-STAT pathway.

The reagent is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples. Phosphorylation at Y645 marks STAT6 activation, making this reagent useful for studies of Th2 lymphocyte differentiation, B-cell IgE class switching, and downstream transcriptional responses in airway epithelial and immune cell models.

Supplied as 100 µl of unconjugated polyclonal antiserum raised in rabbit, the antibody offers flexibility to pair with HRP-, biotin-, or fluorophore-labeled secondary reagents according to the chosen detection chemistry. Intended for research use only.