Anti-STAT4 (Ab-693) Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against Signal Transducer and Activator of Transcription 4 (STAT4) and is designed to detect the endogenous level of total STAT4 protein. The immunogen corresponds to a synthetic peptide surrounding amino acids 691–695 (K-G-Y-V-P) of human STAT4, and antibodies were affinity-purified by epitope-specific peptide chromatography to maximize specificity. Supplied unconjugated at a concentration of 1.0 mg/mL in a 50 µl volume, the antibody is formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant. The product is shipped at 4°C and should be aliquoted and stored at –20°C upon arrival, with repeated freeze/thaw cycles avoided to preserve activity. Validated applications include Western blotting (WB) and immunohistochemistry (IHC), and the reagent has been confirmed to react with Human, Mouse, and Rat samples, making it a versatile option for cross-species signaling research. As a polyclonal primary antibody raised in Rabbit, it offers broad epitope coverage within the target region, which is particularly useful when studying phosphorylation-independent expression of STAT4 in cytokine-driven immune pathways, including IL-12 and IL-23 signaling. The unconjugated format also allows researchers to couple the antibody to their preferred fluorophore or enzyme for downstream detection workflows.