Anti-Stat3 (S691) Antibody

Phosphorylation at serine 691 on STAT3 modulates cytokine and growth factor signaling, and this rabbit polyclonal antibody from Antibodies.com is raised specifically against that phospho-epitope. The unconjugated reagent is supplied at 1 mg/ml in phosphate buffered saline containing 15 mM sodium azide at approximately pH 7.2, packaged in a 100 µl vial sized for multiple Western blot and immunohistochemistry experiments. Confirmed reactivity with human, mouse, and rat samples supports comparative work in cultured cell lines, primary tissues, and animal models of inflammation, oncology, and immune signaling. For JAK/STAT pathway studies, the antibody can be applied to lysates from stimulated cells or to fixed tissue sections, complementing total STAT3 reagents by highlighting the S691-phosphorylated subpopulation. Refrigerate on receipt to preserve activity; the azide-containing formulation permits direct dilution into standard blocking and wash buffers.