Anti-STAT3 Antibody

This Antibodies.com polyclonal antibody specifically recognizes Signal Transducer and Activator of Transcription 3 (STAT3), an ~88 kDa cytoplasmic transcription factor that is phosphorylated at Tyr705 upon cytokine and growth factor stimulation through the JAK-STAT signaling pathway. The unconjugated IgG reagent is supplied as 100 µg in liquid format, validated for Western blot and immunocytochemistry on human, mouse, and rat samples. For best results, aliquot upon receipt and store at -20°C, avoiding repeated freeze-thaw cycles to preserve binding activity. Researchers use this reagent to investigate STAT3 activation, dimerization, and nuclear translocation in cancer biology, inflammation, and innate immune response studies.