Anti-Stat3 Antibody

Raised in rabbit, this unconjugated polyclonal antibody recognizes Signal Transducer and Activator of Transcription 3 (Stat3), a transcription factor that couples cytokine and growth factor receptor signaling to gene expression. Validated across Western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), and ELISA workflows, the reagent from Antibodies.com detects endogenous human, mouse, and rat Stat3 in both denatured and native sample contexts.

The antibody is supplied as 100 µl of affinity-purified serum in a vial, supporting discovery research and target validation studies that probe JAK/STAT pathway activity. Because it is unconjugated, the reagent can be paired with a secondary antibody of the user's choice — HRP, biotin, or fluorescent conjugates — for flexible assay design. Researchers apply this reagent to phospho-Stat3 (Tyr705) signaling studies, cancer cell line panels, and tumor tissue microarrays.

Recommended handling: aliquot upon first thaw to minimize freeze-thaw cycles and refrigerate for short-term use; for longer-term storage, keep frozen. Host species is rabbit; clonality is polyclonal; the target is Stat3. Reactivity confirmed with Human, Mouse, and Rat samples.