Anti-STAT1 Antibody

Raised in Rabbit as a polyclonal immunogen targeting Signal Transducer and Activator of Transcription 1 (STAT1), this unconjugated primary antibody from Antibodies.com is supplied as 100 µl of ready-to-use reagent for western blot and immunohistochemistry workflows. STAT1 serves as the central effector of the JAK-STAT signaling cascade, relaying signals from type I, II, and III interferon receptors to the nucleus, where phosphorylated dimers drive transcription of interferon-stimulated genes. Investigators studying antiviral defense, cytokine responses, and tumor immune evasion routinely deploy this reagent to monitor endogenous STAT1 levels in human cell lysates and formalin-fixed tissue sections. The polyclonal format recognizes multiple epitopes across the full-length protein, which can improve detection when single monoclonal clones miss their target. Compatible with standard chemiluminescent western blot protocols and standard IHC staining procedures, the reagent offers flexibility across discovery and translational research projects.