Anti-Stat1 Antibody

Stat1 (Signal Transducer and Activator of Transcription 1) is a key transcription factor central to JAK-STAT signal transduction and interferon-mediated immunity, making antibodies against it important reagents for laboratories studying antiviral responses, cytokine signaling, and immune regulation. This rabbit polyclonal reagent from Antibodies.com is supplied as a 100 µl aliquot of unconjugated antibody, raised against the Stat1 target and validated for western blot, immunohistochemistry, and ELISA workflows.

The antibody recognizes endogenous Stat1 in human, mouse, and rat samples, supporting cross-species studies in cell culture models, primary tissue lysates, and archival specimens. Researchers commonly deploy this reagent to monitor total and phosphorylated Stat1 levels across interferon-stimulated conditions, tumor microenvironment investigations, and studies of primary immunodeficiencies where Stat1 function is altered. Its unconjugated format allows flexible pairing with user-selected secondary antibodies, fluorophores, or HRP conjugates to adapt to individual experimental designs.

Provided as a liquid polyclonal antibody in a single use vial format, the reagent ships ready to aliquot for short-term refrigeration. Intended for in vitro research use only, this primary antibody integrates into established assay pipelines for signal transduction profiling, viral pathogenesis studies, and characterization of therapeutic candidates targeting the interferon pathway.