Anti-STAP2 Antibody

STAP2 (Signal-Transducing Adaptor Protein 2) is an intracellular scaffolding protein studied for its role in coupling immune receptors to downstream effectors in macrophages, B cells, and T cells. Researchers use this affinity-purified reagent from Antibodies.com to visualize endogenous STAP2 expression across human cell and tissue specimens in western blot, immunohistochemistry, and immunofluorescence workflows.

Produced in rabbits and purified by antigen-affinity chromatography, the polyclonal antibody recognizes epitopes distributed across the human STAP2 sequence, supporting detection of the full-length adaptor in lysates prepared from hematopoietic lines as well as in formalin-fixed tissue sections. The unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary reporters chosen by the end user, and the 100 µl vial provides enough material for routine multi-blot screening campaigns.

Published work on STAP2 has linked it to negative regulation of STAT3, modulation of Fc receptor signaling, and altered responses in certain leukemias and chronic inflammatory states, making the target relevant to groups exploring cytokine signaling, oncology pathways, and innate immune checkpoints. The reagent is supplied as a liquid in PBS-based buffer with stabilizing additives and should be stored refrigerated for long-term use; small aliquots help limit freeze-thaw cycles when the same lot is reused over months of investigation.