Anti-STAG2 Antibody

STAG2 (Stromal Antigen 2) is a core subunit of the cohesin ring complex that mediates sister chromatid cohesion during mitosis and regulates chromatin architecture and gene expression. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against STAG2 and validated for Western blot and immunohistochemistry applications on human samples.

Provided as 100 µl of ready-to-use reagent, the antibody detects endogenous STAG2 protein in cell lysates and formalin-fixed tissue sections. Researchers studying cohesinopathies, acute myeloid leukemia, bladder carcinoma, and Ewing sarcoma biology commonly use anti-STAG2 reagents to assess loss-of-function mutations, subclonal heterogeneity, and cohesin complex integrity in tumor specimens.

The polyclonal format yields recognition of multiple epitopes across the STAG2 protein, supporting consistent staining in IHC and clear bands in WB. Store aliquots at -20 °C and avoid repeated freeze-thaw cycles to preserve activity. Intended for research use only in cancer biology, cell division, and chromatin organization studies.