Anti-STAG2 Antibody

Raised in rabbit and validated for Western Blot detection, this polyclonal IgG preparation from Antibodies.com specifically targets human STAG2 (Stromal Antigen 2), a core subunit of the cohesin ring complex that holds sister chromatids together after DNA replication. Beyond its canonical role in chromatid cohesion, STAG2 participates in chromatin organization, transcriptional regulation, and DNA double-strand break repair, and inactivating mutations in the STAG2 gene are recurrently observed in glioblastoma, acute myeloid leukemia, Ewing sarcoma, and other cancers, making robust immunological detection of the protein useful across oncology research workflows. The reagent is supplied unconjugated in a 200 µl volume, giving researchers flexibility to choose HRP, fluorophore, or biotin labeling chemistries, and the rabbit IgG isotype is compatible with standard anti-rabbit secondary antibodies for immunoblotting of whole-cell lysates prepared from human cell lines or tissue samples.