Anti-ST3GAL2 Antibody

Raised in rabbit against human ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (ST3GAL2), this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as 100 µl and validated for Western blot detection in human samples. The target is a Golgi-resident type II membrane sialyltransferase that transfers sialic acid in alpha-2,3 linkage onto terminal galactose residues on glycoproteins and glycolipids, contributing to disialyl ganglioside biosynthesis, including the GD1α motif.

ST3GAL2 expression is well documented in brain tissue, where it shapes ganglioside profiles tied to neuronal function, and altered ST3GAL2 levels have been reported in glioblastoma cell lines and other tumor contexts in which aberrant sialylation supports invasive growth. The polyclonal host response provides recognition of multiple epitopes on the target, while the unconjugated format lets researchers pair the antibody with their preferred secondary reporter or label it directly for downstream immunoblotting workflows in research use only applications.