Anti-ST3GAL1 Antibody

Raised in rabbit, this polyclonal reagent from Antibodies.com targets ST3GAL1, the type II transmembrane sialyltransferase that catalyzes alpha-2,3-linked sialylation of terminal galactose residues on N- and O-linked glycoproteins and glycolipids. The unconjugated antibody is supplied as 100 µl of antiserum and has been validated for Western blotting, immunohistochemistry, and immunofluorescence on human samples, supporting studies of aberrant cell-surface glycosylation in oncology and probing ST3GAL1 protein expression in tumor tissue.

As a polyclonal reagent, it offers broader epitope coverage than monoclonal alternatives and permits detection of the enzyme in both fixed and frozen tissue sections. Researchers investigating epithelial tumors in which ST3GAL1-mediated sialylation has been linked to invasive and metastatic behavior, including pancreatic ductal adenocarcinoma and colorectal carcinoma, will find this antibody useful for expression profiling and subcellular localization work.