Anti-SSSCA1 Antibody

Raised in rabbit against the Sjögren syndrome/scleroderma autoantigen 1 (SSSCA1) nuclear protein, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as a 50 µl vial volume for Western blot detection in mouse samples. The target is a ~27 kDa nuclear antigen originally characterized through autoimmune sera from patients with Sjögren syndrome and systemic scleroderma, and it remains a useful marker for studies of humoral autoimmunity, nuclear antigen biology, and connective tissue disease mechanisms. As a polyclonal preparation, the antibody recognizes multiple epitopes across the SSSCA1 sequence, an advantage when probing denatured lysates prepared for SDS-PAGE and Western blot workflows. The reagent should be stored refrigerated at 4 °C, aliquoted on first use, and protected from repeated freeze-thaw cycles to preserve binding activity over its shelf life. Researchers investigating autoimmune signatures, chromatin-associated antigens, or scleroderma-related pathways in murine models will find this reagent a specific unconjugated primary antibody suitable for chemiluminescent or chromogenic Western blot readout, paired with an HRP- or alkaline phosphatase-conjugated secondary of choice.