Anti-SRPK1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets SRPK1 (Serine/Arginine-Rich Protein-Specific Kinase 1), a kinase that phosphorylates SR-family splicing factors such as ASF/SF2 and modulates constitutive and alternative pre-mRNA splicing. The reagent is supplied as a 200 µl vial of unconjugated IgG and is validated for Western Blot, Immunohistochemistry, and Immunofluorescence workflows, with reactivity confirmed against human, mouse, and rat samples.

SRPK1 also contributes to viral RNA processing, regulates the nuclear import of signal-dependent transcription factors, and supports genome stability through interactions with chromatin remodeling complexes. The polyclonal format provides recognition of multiple epitopes on the target kinase, supporting reproducible detection in cell lysates, fixed tissue sections, and cultured cells. Aliquot upon receipt and store at -20 °C in working volumes to minimize freeze-thaw cycles and preserve binding activity for downstream applications in splicing biology, viral replication, and signal transduction research.