Anti-SRp20 Antibody

This unconjugated rabbit polyclonal reagent targets SRp20, the smallest member of the arginine-serine-rich (SR) protein family that governs constitutive and alternative pre-mRNA splicing, mRNA nuclear export, and translation control. Distributed by Antibodies.com at 100 µl per vial, the antibody has been validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows and cross-reacts with both human and mouse samples, supporting studies in mammalian cell lines and animal model tissues.

Investigators rely on this reagent to map SRp20 (also known as SFRS3 or SRSF3) distribution across tissue sections, monitor its nuclear relocalization during cellular stress or differentiation, and quantify its upregulation in hepatocellular carcinoma, cervical cancer, breast tumors, and other malignancies where SRSF3 expression is frequently elevated. The polyclonal format increases the likelihood of recognizing multiple epitopes on the SRp20 protein, which is helpful when probing spliceosomal complexes and post-translationally modified forms. Each vial arrives unconjugated, allowing direct conjugation or pairing with secondary detection reagents according to the user's protocol.

For best results, store aliquots at -20 °C and avoid repeated freeze-thaw cycles to preserve antigen-binding activity across multiple experimental rounds.