Anti-SRP19 Antibody

Raised in rabbit and supplied as an unconjugated reagent, the Anti-SRP19 polyclonal antibody from Antibodies.com targets the 19 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the co-translational targeting of nascent secretory and membrane proteins to the endoplasmic reticulum. Validated for Western blot and immunofluorescence workflows, it cross-reacts with both human and mouse samples, supporting studies in cell biology and protein trafficking.

Each vial contains 100 µl of antibody that can be used across multiple experiments. The unconjugated format offers flexibility, allowing researchers to pair the reagent with secondary conjugates of their choice for varied detection strategies, including fluorescence microscopy and chemiluminescent Western blot detection. Refrigerate the antibody between uses and aliquot to preserve activity across repeated experiments.

Beyond general SRP biology, this reagent is also relevant to investigations of SRP biogenesis, the unfolded protein response, and disease contexts where signal recognition particle function is altered, including certain cancers and congenital disorders linked to defective secretory protein trafficking.