Anti-SRI Antibody

Produced by Antibodies.com, this unconjugated primary antibody recognizes sorcin (SRI), a 22 kDa calcium-binding protein known for regulating intracellular calcium homeostasis and modulating ryanodine receptor activity in excitable tissues. SRI is widely investigated in cardiac physiology and in cancer biology, where elevated sorcin expression has been linked to multidrug resistance in leukemia, breast, and lung tumor cell lines, making anti-SRI probes useful for tracking resistance phenotypes and calcium-handling changes in basic research. Validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, the reagent is supplied as 100 µl of polyclonal sera, supporting immunoblotting of cell and tissue lysates as well as chromogenic or fluorescence staining of fixed sections. Researchers studying drug efflux mechanisms, cardiomyocyte calcium signaling, or tumor biomarker discovery can pair this reagent with appropriate secondary antibodies for protein detection across multiple experimental conditions. Store refrigerated and protect from light to preserve reagent activity over the working shelf life.