Anti-SRC (phospho Y416) Antibody

Recognizing the catalytically active form of the SRC non-receptor tyrosine kinase through phosphorylation at tyrosine 416, this rabbit polyclonal IgG antibody from Antibodies.com targets the conserved autophosphorylation residue within the kinase activation loop whose modification correlates with full enzymatic activity. Supplied as 100 µl of unconjugated reagent in a single-use vial, the antibody is validated for Western blot detection of endogenous phospho-SRC in lysates from human and mouse cells and tissues, supporting studies of receptor tyrosine kinase signaling, focal adhesion dynamics, and oncogenic transformation in which Y416 phosphorylation status serves as a marker of pathway activation. As a polyclonal reagent generated in rabbit, the antibody engages multiple epitopes around phospho-Y416, delivering a reliable band in standard immunoblotting workflows with HRP-conjugated secondaries and chemiluminescent or chromogenic substrates. For best results, refrigerate upon receipt, aliquot to limit freeze-thaw cycles, and protect from light during extended storage.