Anti-SR-2A Antibody

Raised in rabbit, this polyclonal reagent targets somatostatin receptor subtype 2A (SR-2A, also known as SSTR2A), a G-protein coupled receptor involved in inhibitory neuroendocrine signaling and widely studied in the context of neuroendocrine tumors and somatostatin analog pharmacology. Manufactured by Antibodies.com as an unconjugated primary antibody, it is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, packaged as a 100 µl vial.

The polyclonal host and unconjugated format suit western blot workflows, where the antibody has been validated against human, mouse, and rat samples. Because somatostatin receptor expression is frequently characterized across species in receptor biology studies, the cross-reactivity profile supports translational work ranging from rodent model tissues to patient-derived material. The 50% glycerol content permits storage at -20 °C without freezing the antibody solid, while the PBS vehicle and azide preservative are compatible with standard immunoblotting buffers.

Research applications include mapping SSTR2A expression in pancreatic and gastrointestinal neuroendocrine tumor samples, profiling receptor changes following agonist or antagonist treatment, and studying receptor internalization and downstream G-protein signaling. The unconjugated format allows end users to pair the antibody with their preferred HRP- or fluorophore-conjugated secondary reagent for chemiluminescent or fluorescence-based western blot detection, and the broad epitope recognition afforded by a polyclonal host can be helpful when probing conserved receptor regions across species.