Anti-SPTLC1 Antibody

Manufactured by Antibodies.com, this primary antibody is a rabbit polyclonal reagent raised against serine palmitoyltransferase long chain base subunit 1 (SPTLC1), a key membrane-bound enzyme that catalyzes the first committed step of sphingolipid biosynthesis. Supplied at 50 µl per vial at a working concentration of 1 mg/mL, the unconjugated IgG preparation has been affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen derived from the C-terminal region of human SPTLC1. The antibody specifically detects endogenous levels of the target protein and is validated for Western blot (WB) applications across human, mouse, and rat samples, giving laboratories broad species coverage for comparative studies of the LCB1 / long chain base biosynthesis protein 1 pathway, also annotated as SPT1 or LCB 1. The product is provided as a liquid in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide, and is shipped at 4°C; upon receipt it should be aliquoted and stored at -20°C, with care taken to avoid repeated freeze/thaw cycles to preserve activity. As supplied by Antibodies.com, this polyclonal, host-rabbit reagent is intended for research use only and is not validated for diagnostic or therapeutic applications, but it offers a reliable option for immunoblotting workflows exploring SPTLC1 expression and regulation in cell and tissue lysates.