Anti-SPTLC1 Antibody

The SPTLC1 protein, also known as serine palmitoyltransferase long chain base subunit 1, catalyzes the rate-limiting first step of de novo sphingolipid biosynthesis. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied as an unconjugated IgG preparation in a 200 µL vial, optimized for western blot detection of the human and mouse target. It supports studies of sphingolipid metabolism, the molecular basis of hereditary sensory and autonomic neuropathy type 1 (HSAN1), and related lipid signaling pathways by enabling confirmation of SPT catalytic subunit expression in cell and tissue lysates. The product is provided as a liquid aliquot to be stored refrigerated for working stock use and protected from light to preserve antibody activity over multiple experiments.