Anti-SPT3 (E203) Antibody

The SPT3 protein, also called SUPT3H, functions as a component of the STAGA transcription coactivator complex, contributing histone acetyltransferase activity and chromatin remodeling during transcription initiation. This rabbit polyclonal reagent from Antibodies.com was raised against an epitope within the E203 region and is supplied unconjugated, leaving detection chemistry, fluorophore, or enzyme label choices open to the end user.

Format and handling: each vial contains 100 µl at approximately 1 mg/ml in phosphate buffered saline (PBS) supplemented with 0.05% sodium azide at pH 7.2. For routine use, store refrigerated at 4°C and protect from light if any downstream conjugation is performed; aliquot before freezing if the antibody will be subjected to repeated freeze-thaw handling, since polyclonal preparations are sensitive to aggregation under such stress.

The antibody has been validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human, mouse, and rat samples, supporting cross-species expression studies of SPT3 in fixed or lysed tissue preparations. Researchers investigating transcriptional regulation, histone modification, or chromatin-associated signaling can use this reagent to probe native SPT3 protein levels in cell culture lysates and tissue sections.