Anti-SPINT1 Antibody

SPINT1 (also known as HAI-1, Hepatocyte Growth Factor Activator Inhibitor type 1) is a Kunitz-type transmembrane serine protease inhibitor that regulates matriptase activity and HGF/MET signaling at epithelial surfaces, where loss of expression has been implicated in tumor invasion and placental insufficiency. This unconjugated rabbit polyclonal reagent from Antibodies.com is supplied at 1 mg/ml in PBS buffer containing 0.1% sodium azide and 50% glycerol, and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples. Each 100 µl vial supports detection of endogenous SPINT1 in cell culture lysates, fixed tissue sections, and permeabilized cells, making it a practical reagent for epithelial barrier studies, pericellular protease regulation, and cancer cell biology research. For best results, store at -20 °C in working aliquots to limit freeze-thaw cycles and preserve antigen-binding capacity over the shelf life of the antibody.